Add EU numbering for human IgG CH Chain Analysis - #5
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Show Edelman/EU indices above the raw ruler in CH Chain Analysis after isotype determination, using IMGT Hu_IGHGnber maps that differ by IGHG1–4 hinge and the IgG2 CH2 deletion. Cover maps and therapeutics (trastuzumab, pembrolizumab, nivolumab, panitumumab, rituximab, adalimumab, b12) with provenance-backed tests. Co-authored-by: Derek Croote <dcroote@users.noreply.github.com>
Drop the IMGT link, bolding, and Edelman/EU definition from the constant-region feature bullet. Co-authored-by: Derek Croote <dcroote@users.noreply.github.com>
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* Add EU numbering row for human IgG CH alignments Show Edelman/EU indices above the raw ruler in CH Chain Analysis after isotype determination, using IMGT Hu_IGHGnber maps that differ by IGHG1–4 hinge and the IgG2 CH2 deletion. Cover maps and therapeutics (trastuzumab, pembrolizumab, nivolumab, panitumumab, rituximab, adalimumab, b12) with provenance-backed tests. Co-authored-by: Derek Croote <dcroote@users.noreply.github.com> --------- Co-authored-by: Cursor Agent <cursoragent@cursor.com>
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Summary
Adds an EU numbering row above the raw residue ruler in CH Chain Analysis when the constant region is human IgG (IGHG1–4). Numbering is applied only after isotype determination, using isotype-specific Edelman/EU maps from the IMGT Hu_IGHGnber correspondence table.
Behavior
EU:ruler (decades, same right-align style as the raw ruler) above the existing 1-based alignment rulerAPI
LAMBS.getHumanIgGEuNumbers(isotype)LAMBS.mapEuOntoConstantAlignment(aligned2, species, isotype)Tests
Provenance-backed coverage against real therapeutics and structures:
node test.js: 779 passed, 0 failed