FiberBrowser 3.0.0

FiberBrowser 3.0 is released together with FiberHMM 3.0, the third
generation of the FiberHMM family, and requires it:
fiberhmm[consensus]>=3.0,<4 (installed with FiberBrowser). Browsing works
without FiberHMM; footprint classes, chemistry detection, consensus BAM
export, DAF-seq runs and re-run advisories need it.

Nanopore Hia5 and DddB users: re-call your BAMs. FiberHMM 3.0 ships new
Nanopore Hia5 and DddB models. Re-call Nanopore Hia5 and DddB BAMs made with
FiberHMM 2.x using FiberHMM 3.0 and reload them. The Library marks BAMs that need it (Needs re-run)
and can re-call DAF-seq runs made in FiberBrowser. See the
FiberHMM 3.0.0 changelog.

What 3.0 includes

• Supported: SV display and splits, the insertion lens and Identify (with the bundled fly TE library and
  Dfam downloads), and the Variants panel (SNPs, local read-supported allele patterns, SVs, splits by allele or
  haplotype).
• Preview, on by default (Show preview features, Settings → Reads & Display): insert-expanded
  (alt-allele) panels. Each way into them has a Preview badge and a Known limitations note that says what
  graduates it. With previews off, a session that uses them keeps everything and offers to turn them on. The
  Footprint classes section of the Footprints panel carries a Preview badge but stays available with previews
  off. See What 3.0 includes.
• NFRs and Synchronise regions (its own rail icon) are in every build, independent of the preview switch.
  Sessions and preferences from earlier 3.0 builds open unchanged.
• The Variants panel has a sequence-variant icon on the rail.
• The guided tour (58 steps) has a Variants section on a second bundled demo (H1 PacBio Fiber-seq around a
  heterozygous 7,471-bp insertion on chr1 whose insert carries a CTCF-footprinted NFR): SNPs in view, a split by
  haplotype (HP tags), the SVs tab and the insert expanded. The user guide and the tutorial cover it.

Downloads

File	For
FiberBrowser-3.0.0-arm64.dmg	macOS on Apple silicon (signed and notarized)
FiberBrowser-3.0.0-Setup.exe	Windows 10 2004+ or 11, x64 (runs in WSL 2). Unsigned, so SmartScreen asks you to confirm.
FiberBrowser-3.0.0-windows-portable.zip	The same Windows app without the installer (run Install.cmd)
FiberBrowser-3.0.0-wsl-amd64.tar.gz	The WSL distro on its own, for wsl --import
fiberbrowser-3.0.0 wheel / sdist	pip install fiberbrowser (Linux, macOS, WSL)

The desktop apps bundle FiberHMM 3.0.1. Checksums are in SHA256SUMS.txt.

The full list of changes is in the CHANGELOG.