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Complete Plot Results Index (AG70)

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1. Survival Curves Comparison

Analysis of survival probability across methodologies.

Real Data - Survival Plots

• Hernan:
• Dynamic CC:
• Pierce:
• Landmark (Primary ITT):
• Landmark (Sens. PP):

Reclassified Simulation - Survival Plots

• Hernan:
• Dynamic CC:
• Pierce:
• Landmark (Primary ITT):
• Landmark (Sens. PP):

Null HR=1 Simulation - Survival Plots

• Hernan:
• Dynamic CC:
• Pierce:
• Landmark (Primary ITT):
• Landmark (Sens. PP):

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2. Delta RMST (ΔRMST)

Absolute difference in days of life gained or lost between groups.

Real Data - Delta RMST

• Hernan:
• Dynamic CC:
• Pierce:
• Landmark (Primary ITT):
• Landmark (Sens. PP):

Reclassified Simulation - Delta RMST

• Hernan:
• Dynamic CC:
• Pierce:
• Landmark (Primary ITT):
• Landmark (Sens. PP):

Null HR=1 Simulation - Delta RMST

• Hernan:
• Dynamic CC:
• Pierce:
• Landmark (Primary ITT):
• Landmark (Sens. PP):

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3. Delta-Delta RMST (ΔΔRMST)

Comparison of ITT vs Per-Protocol bias and crossover effects.

All Delta-Delta RMST Comparison Plots

• Dynamic CC (Real):
• Dynamic CC (Reclassified):
• Dynamic CC (Sim):
• Landmark (Real):
• Landmark (Reclassified):
• Landmark (Sim):

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4. Hazard Ratios (Dynamic CC Only)

Instantaneous risk comparison.

Hazard Ratio Plots

• Real Data:
• Reclassified:
• Simulation:

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5. Category by Methodologies

AC) Hernan Style Pooled Logistics

• Real Data (AG70):
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• Reclassified (5% UVX):
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• Simulation (Null HR=1):
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AE) Empirical Dynamic CC RMST

• Real Data (AG70):
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• Reclassified (5% UVX):
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• Simulation (Null HR=1):
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AE) C.S. Pierce Evidence Weighted RMST

• Real Data (AG70):
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• Reclassified (5% UVX):
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• Simulation (Null HR=1):
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AE) Landmark RMST

• Real Data (AG70):
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• Reclassified (5% UVX):
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• Simulation (Null HR=1):
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6. Appendix: Distributions and General Results

Dose Schedules and UVX Plots

• Daily Dose Schedule:
• Interval Histogram:
• UVX Reclassified (Daily):
• UVX Reclassified (Weekly):
• Under Construction: