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v1.6.0: streamlined figure set for the revised manuscript

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@guokai8 guokai8 released this 13 Oct 14:38

Streamlined figure set for the revised manuscript, "Prespecified cross-cohort testing localises an astrocyte-compartment ALS signature to a multicellular myeloid–glial response in the spinal ventral horn".

New in v1.6.0

  • scripts/figures_v2/compose_figures_v3.R: assembles the submitted figure set from saved panel objects.
    • Five main figures: design; single-nucleus replication and confounders; bulk hold-out; cell source; ventral-horn response with a working model.
    • Eight supplementary figures.
    • The source data of each contributing panel are copied next to the assembled figure.
  • Figure scripts: each now saves its panel objects (save_panels in fig_common.R). Two panels store their annotation positions as data columns, so that saved panels are self-contained.
  • README (figure workflow and article title) and CITATION (v1.6.0) updated.

Run the figures_v2 scripts first, then compose_figures_v3.R. Analysis scripts are unchanged from v1.5.0. No data are included.