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v0.2.4

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@github-actions github-actions released this 09 Jul 22:41

[0.2.4] - 2026-07-10

Device-resident trunk for tt-bio gen (BoltzGen) — no structure-model code changed for
Boltz-2/ESMFold2/Protenix-v2 (the new TokenDistanceRecycle/TrunkModule params default to
off/None, purely additive).

Release gate (scripts/release_gate.py, examples/prot.yaml, 200 steps / 5 samples, seed 0):

model CA-RMSD TM floor result
Boltz-2 1.43 Å 0.944 ≤3.0 Å / ≥0.75 PASS
ESMFold2 2.76 Å 0.798 ≤4.0 Å / ≥0.65 PASS
ESMFold2-fast 1.74 Å 0.907 ≤4.5 Å / ≥0.60 PASS
Protenix-v2 3.87 Å 0.706 ≤6.0 Å / ≥0.50 PASS

No regression vs 0.2.3 (within TT diffusion's seed-to-seed variance band).

BoltzGen designability — n=8 fixed-length-100 designs, examples/binder.yaml: scRMSD
median 0.84 Å (resident) vs 0.91 Å (host), 7/8 designs ≤2 Å strict pass (comparable to host's
8/8) — no regression. Wall-clock (design + refold + confidence + analysis + filtering) 697 s
→ 479 s, ~31% faster
. See docs/boltzgen-resident-trunk.md.

Added

  • BoltzGen device-resident trunkTokenDistanceRecycle (mirrors TemplateRecycle) keeps
    the per-iteration token-distance injection fully on-device, collapsing 4 host↔device
    crossings/iteration to 2 (only the template sub-module still round-trips). Boltz.__init__
    takes use_resident_trunk: bool = True; set false to fall back to the original host path.

Changed

  • Promoted Protenix-v2's diffusion denoiser-unit and AttentionPairBias(has_s=True) ad-hoc
    checks to proper pytest cases (test-coverage only, no functional change).