Codeine v0.1.0

First public release of Codeine.

Includes:

• CodingSpace for exact counting, enumeration and sampling of synonymous coding sequences.
• MutationSpace for designing synonymous variants around a reference sequence.
• TranslationTable with support for custom and NCBI genetic code tables, as DNA or RNA.
• CodonWeights with custom and built-in species-specific codon usage tables.

Features:

• Built-in sequence constraints:
  • Forbidden motifs (e.g. restriction sites)
  • Maximum homopolymer length
  • Fixed codons
  • Sequence contexts
  • Mutation distances
• Exact constrained sequence generation by construction (no post-generation filtering).

Also includes full API documentation and user guide on Read the Docs.