varcode 7.0.0

v7.0.0 (2026-07-08)

Changed

• The default effect annotator is now fast (the offset-based
  classifier varcode has shipped since 2.0.0) instead of protein_diff.
  Variant.effects() / VariantCollection.effects() with no explicit
  annotator= now route through fast. This is a behavior change for
  callers that relied on the default: for SNVs / indels / MNVs the two
  annotators are fully reconciled (see tests/test_protein_diff_parity.py,
  tests/test_annotator_parity_adversarial.py, and
  tests/test_annotator_divergence_scenarios.py), so nearly all output is
  unchanged, but any residual divergence now resolves to fast's
  classification. protein_diff stays available via
  annotator="protein_diff" or varcode.use_annotator("protein_diff"), and
  remains the substrate the MutantTranscript / splice-outcome / germline
  machinery builds on. Rationale: fast is the more battle-tested path —
  during the protein_diff bring-up it was effectively the correctness oracle
  protein_diff was reconciled against
  (#318–#321),
  and it has the cleaner bug history
  (#397). Major version bump
  because default behavior changes.

Added

• Regression pins in tests/test_annotator_divergence_scenarios.py for the
  frameshift coincidental-shared-suffix class
  (#396 /
  #397): a frameshift whose
  novel C-terminus coincidentally ends with the reference protein's terminal
  residue(s) must retain the full tail under both annotators (CFTR
  p.L127fs on the + strand, BRCA1 p.R71fs on the − strand).