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📦 Package
The goal of openVBE is to provide a toolbox for assessing virtual bioequivalence (VBE) of Open Systems Pharmacology Suite models.
You can install the development version of openVBE like so:
# Packages handy for installing a Github package
# install.packages(c('remotes', 'devtools', 'pak'))
pak::pak("abdullahhamadeh/openVBE")If you wish to use the package bundle instead, Linux and Windows bundles are available as zipped artifacts of the Main-Workflow github action.
The method provided in openVBE are detailed in a peer-reviewed article entitled An open-source framework for virtual bioequivalence modeling and clinical trial design, published in CPT: Pharmacometrics & Systems Pharmacology.
How to cite:
Hamadeh et al. An open-source framework for virtual bioequivalence modeling and clinical trial design. CPT. 2025. PSP-2025-0079
Two articles develop case studies of VBE workflows:
To report bugs 🐞 or request potential features 💡, please use the issue tracker.