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Scripts used in the study by Chari et al, Nature Methods, 2015

Description of each file:

storeAlterations.targets.indelsOnly.py - python script that outputs mutation rates from the integrated target dataset. Pileup files should be split on a per target basis to speed up run time. Prior to running this script, run the "splitPileup.py" on the aggregate pileup file containing all six samples.

splitPileup.py - python script to split a pileup file into individual files for each target site

Illumina.Scoring.Targets.txt - score file used by the storeAlterations script to use base quality scores for filtering

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Software package which allows a user to identify and score sgRNA sequences based on activity

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