V2.1.0

This minor version presents a couple of changes that improve the integration of
RAMEN with GenomicRanges objects and Bioconductor:

• findVML() outputs a GRanges object for the identified VML instead of
  a data frame.
• Downstream functions (i.e., summarizeVML(), findCisSNPs(),
  selectVariables(), medCorVMR() and nullDistGE()) now take GRanges
  objects as an input, instead of data frames. The argument name changed from
  "VML_df" to "VML". When appropriate, the output is now also a GRanges object.
• summarizeVML() now outputs a matrix instead of a data frame.

In addition to that, the Vignette has been improved. New sections have been
added to provide guidance and recommendations to the users (e.g regarding data
pre-processing andexpectations, as RAMEN expects all data to be alread cleaned,
quality checked, and pre-processed). Also, some sections have been improved to
provide clearer instructions.

This minor version also has multiple improvements to the code, which present no
changes in the user front but have a positive impact on the internal functioning
of the package, such as:

• Optimized examples with reduced running time.
• Reduced dependencies in the package. The installation time has been
  significantly reduced.
• Implemented internal helper functions to improve the readability of the code
  and improve its debugging.
• Reduced data casting and conditionals inside the functions.
• Improved error messages across all functions.

These changes were motivated by the rOpenSci peer review process.

What's Changed

• Incorporated rOpenSci reviewer's suggestions (1st round) by @ErickNavarroD in #5

Full Changelog: v2.0.1...v2.1.0