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Mar 21, 2023
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Nice work. some minor comments before merge. Especially the test might need some improvement.
…utside of the loop
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Reference Issue or PRs
Fixes #95
What does your PR implement? Be specific.
When each gene has at least one zero, it is not possible to compute size factors using the median of ratios method.
This PR implements an iterative MLE scheme to fit size factors when this happens (see #95).