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v1.1.3

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@sebastian-gregoricchio sebastian-gregoricchio released this 09 Jul 10:41

v1.1.3 - July 8th 2026

  • harmonize.batches(): added algorithm (ComBat/limma), ComBat.mode, and block; limma helps on sparse designs where ComBat hits a singular matrix
  • harmonize.batches(): drop uncorrectable proteins with a warning, error on an empty result, and fix the algorithm/block defaults
  • load.counts2 automatically converts the counts into log2 transformed.
  • diff.analyses, diff.analyses.limma and diff.analyses.prolfqua now return, for each group, the standard deviation (sd.<group>) and standard error of the mean (sem.<group>) of the log2 expression values, plus lfcSE, the standard error of the log2(FoldChange). The new columns are appended at the end of the results table. lfcSE is NA when stat.test = "wilcoxon"
  • updated manual and vignette accordingly to take into account for these exceptions and modifications

Full Changelog: 1.1.2...1.1.3