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Curiosity in exploring the chemical space

This repository contains the code to reproduce experiments of "Curiosity in exploring the chemical space: Intrinsic rewards for molecular reinforcement learning"

Setup

Install by cloning the repository and creating a environment using the requirements.txt

conda create --name intrinsic_rewad_mol_rl --file requirements.txt
conda activate intrinsic_rewad_mol_rl

Example experiment

Run an experiment using

python chem_ppo_parallel.py --intrinsic_reward_weight 0.1 --plot True --scoring_fnc PLOGP --discount_factor 1 --batch_size 64 --k_epochs 4 --intrinsic_reward_type COUNTING

which trains an RL agent to optimize the pLogP score using the count based intrinsic reward with a reward weight of 0.1 For the different reward types this should reproduce molecules similar to these ones

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