v0.1.0 - Production-Oriented Biomedical KB Foundation
This release publishes Biomedical Agent DB Karpathy as a production-oriented
foundation for LLM-assisted biomedical knowledge-base construction.
Included
- PostgreSQL relational core for entities, names, xrefs, relations, evidence,
source releases, ingest runs, and variant context. - Numbered initial schema migration at
schema/migrations/001_initial_core.sql. - Installable Python package with
pyproject.toml. biomedkb normalize-hgncCLI for converting HGNC complete-set CSV/TSV rows
into provenance-aware NDJSON.- HGNC normalization library preserving approved symbols, aliases, previous
symbols, common xrefs, source release metadata, and ingest run metadata. - Unit tests for HGNC normalization and CLI output.
- GitHub Actions CI across Python 3.10, 3.11, and 3.12.
- Agent behavior rules for cautious biomedical normalization.
- MIT license, citation metadata, and privacy/no-telemetry statement.
Scope
This is not a complete biomedical database dump. It is the first production
foundation: schema, package, CLI, tests, CI, provenance model, and one working
source normalizer. Additional source pipelines can build on the same contracts.
Recommended Next Pipelines
- MONDO diseases and synonyms.
- ClinVar variant assertions with review status and disease links.
- PubMed paper metadata for evidence provenance.
- UniProt protein records and gene/protein xrefs.
- ChEBI/PubChem chemical normalization.