Predictive mathematical modeling is an essential part of systems biology and is interconnected with information management. Systems biology information is stored in specialized formats http://co.mbine.org that facilitate data storage and analysis (e.g. http://sbgn.org, http://sbml.org). These formats are not designed for easy human readability and thus require specialized software to visualize and interpret results. There is an RDF/XML schema for storage of each type of data. Traditionally, to understand this data, you need specific tools that perform a specific set of queries. AI allows users to explore different type of data directly https://www.nature.com/articles/s41540-025-00496-z. We prototyped a ChatGPT chatbot to explore VCell models http://vcell.org. The design of the Chatbot is described in the following presentation. It is using VCell API.