What changed
- Adds the complete GEO accession ? processed expression ? frozen score route for 15 public input files, 10 data sets, and 92 biological samples.
- Deposits the missing frozen manifests, sample-level derived source data, preprocessing parameters, fold coefficients, and clean-run evidence.
- Reproduces 60/60 v1.2 scores, 100/100 v1.3 scores, and 816/816 estimable v2 module scores; all 12 frozen non-estimable states are retained.
- Repairs Fig 1 text overflow and corrects the Fig 4/S1 production dimensions.
- Restricts the cross-run fixed hash registry to six substantive numerical outputs; timestamped run summaries remain auditable but intentionally have run-specific hashes.
No model was refit or retuned, no threshold or test was changed, and no scientific conclusion changed. The locked conclusion remains that directional responsiveness was observed but HCC-senescence specificity was not established.
Tagged commit: 5bbe6a207ed01a230a1c86adbddd4de6dd277361
Audited standalone archive SHA-256: 8cce9c2ffda0cf4203a7239d6f6e75f51647ea087f5d014a320594a4fa57eecf