CellCounter 1.0.10 (macOS)
CellCounter 1.0.10 for macOS adds a native microscopy workspace for multidimensional exploration, reproducible processing, and presentation. It requires macOS 15 or later and runs natively on Apple silicon and Intel Macs.
New microscopy workspace
- Browse time, Z, channel, and other dataset axes through a persistent layer-based workspace.
- Open local multiscale OME-Zarr / OME-NGFF datasets and plates with automatic viewport-appropriate resolution selection.
- Register image layers, assemble tile mosaics, and create or manually correct cell lineages.
- Paint multiclass training labels and export 16-bit masks for model-training workflows.
- Record and replay local workflows for layer, axis, registration, and stitching operations.
- Build keyframed animations of dataset axes, camera position, visibility, and opacity.
- Inspect bundled capabilities through a curated extension catalog that does not execute third-party plugin code.
Speed and reliability
- Large image sequences load their current and adjacent planes on demand instead of decoding every frame.
- OME-Zarr metadata, chunks, planes, and workspace previews use byte-bounded caches and explicit resource limits.
- Lineage matching uses a spatial index; the large regression fixture performs over 4,000 times fewer distance comparisons than exhaustive matching.
- Registration, stitching, export, and document persistence run outside the interface where possible and support progress and cancellation.
- Stitching accounts for output, coverage, input, and preview memory before allocating a mosaic.
Validation
- The complete macOS unit, performance, and UI test suite passed, including all four UI checks.
- The archive contains both
arm64andx86_64and passes strict deep code-signature validation. - ZIP SHA-256:
679ce5b7fd07fc62d83ff245e510fff92399617e6f090e2e4ede038de124c596
Install
Download CellCounter-v1.0.10.zip, unzip it, and move CellCounting.app into Applications. This build is ad-hoc signed but not notarized, so macOS may require System Settings → Privacy & Security → Open Anyway on first launch.
Existing projects, model environments, masks, and corrections remain in place during upgrade. Image processing remains local; CellCounter does not upload microscopy images.