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Bis adamantane cylam

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Klementine Burrell-Sander edited this page Oct 7, 2021 · 4 revisions

Synthetic route

Full bis-adamantyl cyclam synthesis

Steps

Bridging of cyclam

Bis-propargylation of bridged cyclam

Bis-propargyl cyclam bridge removal and boc protection

Azidoadamantane synthesis

Azidoadamantane and bis-proparygl cyclam click-coupling

Bis-adamantane cyclam deprotection

Social Network Analysis

Antibiotics Networks

Malaria Networks

Mycetoma Networks

Tuberculosis Networks

Open Source Drug Discovery Networks

Cyclam with Adamantyl or Ferrocenyl Pendant Groups

Bis-adamantane cylam

Bis-ferrocene cyclam

Open Cyclam with Adamantyl or Ferrocenyl Pendant Groups

Bis-adamantane linear polyamine

Bis-ferrocene linear polyamine

DOS Linear Amines

Acylation route

Allylation route

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