OSP Suite Version 12 Update 3 released

You can download the version here.

Release Notes for the Open Systems Pharmacology Software Suite 12 Update 3

Fixed issues and Improvements

PK-Sim

• Allow import/export of building blocks to snapshot in standard mode
• Parameter view - make the user settings layout apply to all instances
• Load compound from snapshot error in developer version
• Cloning a time profile in simulation loses many settings
• Cloning a population simulation retains the old simulation name in the legend
• Reset of distributed individual parameters in a simulation does not work
• Modified parameters not exported to snapshot
• Create Compound UI destroyed

MoBi

• Check for NaN and Inf values upon creating a model configuration
• Comparison table - show formula types when they differ
• Remove classifications when removing modules
• For multiple doses, improve how applications are organized using presentation
• Renaming molecules to existing molecule names causes validation to fail
• Add user setting for default parameter grouping
• Create context menu for adding initial conditions
• After a simulation runs, the highlighted simulation should not change
• When cloning a simulation, the observed data is not enabled in the chart by default
• It is possible to create a duplicate formula with the same name
• Automatic rename of like-named reactions
• Renaming reactions on load should update formula paths
• PKML export default file name
• Parameter Values building block: parameters of reactions are not shown when creating new parameter value
• Undo of change molecule start amount does not revert extension module back to PK-Sim module
• Event assignments: parameters from individuals are not displayed when changing entity
• Parameters from reactions are not listed in the possible referenced objects
• Make reaction parameters accessible to the parameter value building block references to add
• Molecule properties are not added to molecules
• "Events" should not be allowed as name for any container
• Import of molecular start values from Excel sheet does not overwrite existing start values

PK-Sim and MoBi

• Export history to CSV or other text format
• New dimension: Area per amount per time
• New dimensions: Amount per area and inversed area
• Separator selector is styled differently and pops under PK-Sim
• Add output path metadata to observed data imports
• Make preview option sticky in projects
• Parameter identification options not visible on small screens
• Include possibility of filtering by user-defined parameters for sensitivity analyses and parameter identifications
• When creating a new initial condition, value should default to 0 instead of not available
• Run and some other actions are not disabled in the context menu after a parameter identification was started
• Reload with same settings fails if sheets were removed
• Transferring parameter identification results to simulation doesn't work well when using "use as factor" option
• Comparison table for building blocks - show name of the module
• Remove check for monotonically increasing time values in data repository
• Allow multiple data points with the same time within observed data set
• Cancelled parameter identification does not show number of evaluations
• Parameter identification: erroneous behavior of transfer results to simulation in combination with use as factor

New releases of OSP Platform qualification library and PBPK Models Library

As with every new OSP Suite release, ALL platform qualification reports and model evaluation reports have been recreated with the new version of the OSP Suite:

• OSP Qualification Reports library
  • See the Release Notes for a full list of changes.
• OSP-PBPK-Model-Library
  • See the Release Notes for a full list of changes.

New release of the ospsuite R package

• Installation and new features: see here
• Documentation: see here