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Structural and Functional Basis of Neuronal Plasticity — Healthy Control (HC) Group

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@data-hcp data-hcp released this 22 Oct 19:33
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Learn about vigilant mode.

License

Creative Commons Attribution 4.0 International (CC BY 4.0)

Source

https://zenodo.org/records/15149088
Contact: davide.dicenso@unich.it
Data from Healthy Controls (HC) group

Overview

This dataset includes imaging data from the Healthy Control (HC) group of the project “Structural and Functional Basis of Neuronal Plasticity.”
It was designed to investigate cerebral blood flow (CBF) and metabolic responses to motor learning using multimodal MRI techniques.

We developed an MRI protocol combining Diffusion-Weighted Imaging (DWI) and pseudo-continuous arterial spin labeling (pCASL) with pre-saturation, background suppression, and a dual-excitation (DEXI) readout.
This protocol enables mapping of CBF and absolute CMRO₂ during resting states and after motor task learning within the MRI scanner.

Dataset Information

Category Details
Subjects 40 healthy controls
Scanner Siemens Prisma 3T (Siemens Healthineers, Forchheim, Germany)
Head Coil 32-channel receive-only
Anatomical Scan T1-weighted MP2RAGE
Functional / Perfusion Scans 3 DEXI pCASL acquisitions
Diffusion Scans 2 DWI acquisitions
Metabolic Scans TRUST and IR-EPI acquisitions for brain metabolic metrics

Task Description

Participants performed a visuomotor matching task inside the MRI scanner:

  • A white circle expanded and contracted on a black screen.
  • Participants controlled a green circle using an MRI-compatible data glove (Fifth Dimension Technologies, Pretoria, South Africa) to match its size to the white circle.
  • The task included 15 blocks (7 fixed-sequence, 8 random), each lasting 35.2 s, followed by 26.4 s of rest.
  • Stimuli were presented using PsychoPy.

Additional Collected Data

Neuropsychological assessments, end-tidal CO₂ and O₂ traces, and task performance metrics were also recorded.
These datasets are currently being converted and analyzed and are not yet included in this release.

Known Missing or Partial Data

  • sub-001–010: No SWI images (SWI introduced starting from sub-011)
  • sub-011, sub-013: Fewer DWI directions in second run due to scanner issue
  • sub-020: No SWI images
  • sub-025: Presence of an arachnoid cyst
  • sub-027: Did not complete protocol
  • sub-030, sub-032, sub-033, sub-039: Dropouts
Assets 574
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