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esvee v2.0

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@hmftools-release-bot hmftools-release-bot released this 08 Jun 21:27
· 230 commits to master since this release

Functional:

  • support for SBX and Ultima
  • allow mismatches in line test ref bases
  • prevent short local links in alignment interpretation for requeried alignments
  • read ref base check matching seed multiple times requires non-low-base matches
  • fixed min qual to test sequence comparisons
  • ensure +/- orientation in assembly links for indels
  • mark line reads only if ref base A/T repeats <= 20
  • prep filter supps with low map qual (<10) and trimmed align length < 40
  • require less than 1/3 bases as low-qual errors to add junction read, capture low-qual mismatches prior to consensus base determined
  • fixed read parse state invalid, used by ref seq building
  • add junction read check max repeat count diff
  • soft-filter off-target variants

Technical:

  • filter phase groups if assembly count exeeds 1k
  • only support loading a single junction file