linx v2.3
·
230 commits
to master
since this release
Functional:
- deletion bridge check for adjacent now considers orientation
- somatic dup-dels in 3'UTR can be disruptive
- fusions restored enchancer 3' upstream distance to 250K
- set driver reported status using likelihood
- required 1mb distance for enhancer prom fusions, check known exons if set to be high impact prom
- highly impact exon fusions ignore chain termination and downstream distance rules
- enhancer fusions without 3' strand can be upstream or coding, within 50K of gene
- known fusions IG changed to enhancer, allow orientation to be 0 meaning not checked
Technical:
- reportable vis plots use simpler naming convention
- removed fusion fields only for patient reporter since can be derived from breakends