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redux v2.0

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@hmftools-release-bot hmftools-release-bot released this 08 Jun 21:29
· 230 commits to master since this release

Functional:

  • support for SBX and Ultima
  • jitter UMI duplicate collapsing allows no edit distance
  • write msi model prediction file if configured
  • support MSK UMIs (variable length)

Bugs:

  • fix failing to plot BQR due to BQR file columns renamed from lowerCamelCase to UpperCamelCase

Technical:

  • runs BQR instead of Sage
  • removed use of jitter read cache
  • refactored jitter duplicate and poly-G UMI collapsing
  • optimised read cache for intense regions (> 100K reads per 400 bases)
  • add R dependencies for BQR plot to Dockerfile

Config:

  • sequencing_type
    -msi_model_error_rates - per cohort
    -msi_model_coefficients - uses HMF WGS cohort
  • support umi_type MSK
  • support umi_type KAPA