Canu is a hierarchical assembly pipeline which runs in four steps:
- Detect overlaps in high-noise sequences using MHAP
- Generate corrected sequence consensus
- Trim corrected sequences
- Assemble trimmed corrected sequences
The easiest way to get started is to download a release.
Alternatively, you can also build the latest unreleased from github:
git clone https://github.com/marbl/canu.git cd canu/src make -j <number of threads>
The unreleased tip has not undergone the same testing as a release and so may have unknown bugs or issues generating sub-optimal assemblies. We recommend the release version for most users.
Brief command line help:
Full list of parameters:
- Koren S, Walenz BP, Berlin K, Miller JR, Phillippy AM. Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation. Genome Research. (2017).