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thresholds argument and CRAM

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@brentp brentp released this 24 Oct 18:55

0.2.0

  • ~2X speed improvement for CRAM by not decoding unused base-qualities.
  • add new --thresholds argument. See README for usage. thresholds and quantization are highly recommended over
  • when using quantize, labels now indicate the range of depths encompassed by that region.
  • for quantize and per-base, mosdepth will output all chromosomes in the bam header, even if they have no alignments.
    this makes it so that mosdepth output for files aligned to the same reference have the same number and order of chromosomes
    and same total base coverage
    per-base output when possible as they are more compact and faster to output.
  • fix bug with dist output for chroms larger than 2.1 billion bases that also affected total output in some cases.