-
Notifications
You must be signed in to change notification settings - Fork 0
CORGIAS Network
The CORGIAS Network displays phylogenetically informed associations among SAR11 orthogroups, calculated with CORGIAS from the current 542-genome orthogroup matrix and rooted bac120 phylogeny.
The network contains 18,606 significant associations among 2,987 OGs after multiple-testing correction: 18,403 positive associations and 203 negative associations. Node labels and functional annotations are read from the current og_suggest.tsv summary.
Nodes represent orthogroups and are colored by COG functional category. Edges summarize statistically supported relationships:
- Red indicates a positive correlation or co-occurrence.
- Blue indicates a negative correlation or anti-occurrence.
- Edge width represents
-log10(q-value); thicker edges indicate stronger statistical support.
- Enter a center OG ID such as
OG0001059. - Set Depth to control how many network steps are included.
- Set the Significance (-log10 q) threshold to exclude weaker edges.
- Set Max nodes to limit the rendered network.
- Press Show network.
The status line reports the total, selected, and visualized node counts. If the network is slow or visually crowded, reduce its depth, increase the significance threshold, or lower the maximum node count.
The CORGIAS result table lists all 18,606 significant associations and is ordered by ascending q-value by default. Search OG IDs or representative COG and KO annotations, or sort the table by association direction, p-value, q-value, or -log10(q-value). Select an OG ID to open its integrated information page. The complete table can also be downloaded as TSV.
Hover over network elements to inspect orthogroup and annotation information. Use Export PNG for a figure or Export JSON for the currently extracted network.
CORGIAS relationships are phylogenetically informed statistical associations and should not by themselves be interpreted as direct physical interactions or evidence of a shared operon. Use Neighboring Genes or the Neighboring Network to examine genome context.