DEEPN 26v7

Python 3 / PyQt5, native Apple Silicon port of DEEPN.

New in v7: Stat Maker rebuilt again - runs DESeq2 twice per collation (raw counts + poscounts, and normalized PPM per Y2H-SCORES) giving both p-value_raw and p-value_norm; hit-criteria panel's Enrichment Fold filter replaced with a dual AdjEnr+DESeq2 agreement gate (locked defaults: in-frame:Forward>=80%, AdjEnr>0, DESeq2 log2FC>3x, p-value_raw<=0.01, P>0.8); new per-bait Matches results table; fixed a bug where single-bait (no Bait2) runs silently produced blank AdjEnr/P values. DEEPN's own Stat Maker button and the Stat Maker window title now both correctly read "v7" (previously unversioned / stuck at v3).

Assets

• DEEPN_26v7_macOS.zip - the main app (unzip and run, self-contained)
• StatMaker_26v7_macOS.zip - Stat Maker as a standalone app (also bundled inside DEEPN itself under Analyze Data)
• lists_data.zip - hg38GeneList.prn and mm10GeneList.prn, excluded from the git repo (exceed GitHub's 100MB file limit). Only needed if building/running from source - unzip into lists/. Already included inside the prebuilt app bundles above.

Stat Maker v7 (standalone)

Standalone build of Stat Maker - matches the copy bundled inside DEEPN 26v7 (see that release's notes for what's new).

Assets

• StatMaker_26v7_macOS.zip - the app (unzip and run, self-contained)
• lists_data.zip - hg38GeneList.prn and mm10GeneList.prn, excluded from the git repo (exceed GitHub's 100MB file limit). Only needed if building/running from source - unzip into lists/. Already included inside the prebuilt app bundle above.

DEEPN 26v6

Python 3 / PyQt5, native Apple Silicon port of DEEPN. New in v6: MAPster
(HISAT2 alignment) bundled as a launchable module with MAPster/MAP+GC+JM
buttons under Process Data, pre-setting genome and output folder from the
selected library.

Assets

• DEEPN_26v6_macOS.zip - the main app (unzip and run, self-contained)
• StatMaker_26v1_macOS.zip - Stat Maker as a standalone app (also
  bundled inside DEEPN itself under Analyze Data)
• lists_data.zip - hg38GeneList.prn and mm10GeneList.prn, excluded
  from the git repo (exceed GitHub's 100MB file limit). Only needed if
  building/running from source - unzip into lists/. Already included
  inside the prebuilt app bundles above.

Stat Maker v3 (standalone)

Standalone Stat Maker v3 - DESeq2 3-way comparison (Bait1 + Bait2 + Vector,
specificity contrast) plus the original Bayesian/MCMC method via JAGS,
reverted to the pre-1.6-0 model (identifiability fixed for single-replicate
baits - see r_scripts/deepn_bayesian_src/README.md in the source tree).

Requires JAGS 4.x installed separately (the app's own "Verify R + JAGS
Installation" button walks through this) - CRAN's rjags rejects JAGS 5.x,
so Homebrew's jags formula won't work; use the official installer.