isoform-analysis

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ADUSlab / isoTOP

A Python tool that detects driver isoforms by measuring topological perturbations in isoform-resolved protein interaction networks. Combines domain-gated PPI inference with augmented Forman-Ricci curvature and a compact classifier on per-sample geometric features.

bioinformatics alternative-splicing network-biology forman-ricci-curvature isoform-analysis

Updated Jun 1, 2026
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charliekim97 / isoform-dominance-pipeline

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Config-driven, CI-tested pipeline for isoform-usage quantification from bulk RNA-seq (Salmon + paired statistics).

python bioinformatics rna-seq reproducible-research alternative-splicing command-line-tool alternative-splicing-analysis transcriptomics salmon bulk-rna-seq isoform-analysis

Updated Jun 17, 2026
Python

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