PHF6
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
2023-02-03 : Thomas : BL
| Entity | Tier | Description |
|---|---|---|
 |
1 | high-confidence BL gene [@thomasGeneticSubgroupsInform2023] |
 |
3 | Retired, Failed QC[@reddyGeneticFunctionalDrivers2017] |
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 7.16 |
| BL | Thomas cohort | 5.50 |
| BL | Panea cohort | 5.90 |
| DLBCL | GAMBL genomes | 2.49 |
| DLBCL | Schmitz cohort | 1.49 |
| DLBCL | Reddy cohort | 1.40 |
| DLBCL | Chapuy cohort | 0.85 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | Yes | 10.853 | 196.689 |
| DLBCL | No | No | 6.130 | 36.559 |
| FL | No | No | 31.614 | 0.000 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
Reddy_2135T Reddy_2190T Reddy_2191T Reddy_2470T Reddy_2475T Reddy_2482T Reddy_2628T Reddy_2764T Reddy_2778T Reddy_2788T Reddy_3403T Reddy_3422T Reddy_3508T Reddy_3548T Reddy_3557T Reddy_3603T Reddy_3725T Reddy_3955T Reddy_823T
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