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TP53
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timeline
title Publication timing
2004-03-01 : Wilda : BL
2011-07-27 : Morin : FL
2012-08-27 : Rossi : MZL
2013-11-05 : Be : MCL
2018-05-31 : Tiacci : PMBL
Entity | Tier | Description |
---|---|---|
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1 | high-confidence MZL gene[@rossiCodingGenomeSplenic2012c] |
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1 | high-confidence PMBL/cHL/GZL gene[@tiacciPervasiveMutationsJAKSTAT2018b] |
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1 | high-confidence BL gene [@wildaInactivationARFMDM2p53Pathway2004] |
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1 | high-confidence DLBCL gene[@lohrDiscoveryPrioritizationSomatic2012a] |
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1 | high-confidence FL gene [@morinFrequentMutationHistonemodifying2011] |
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1 | high-confidence MCL gene [@beaLandscapeSomaticMutations2013] |
Entity | source | frequency (%) |
---|---|---|
BL | GAMBL genomes+capture | 45.50 |
BL | Thomas cohort | 41.90 |
BL | Panea cohort | 43.60 |
DLBCL | GAMBL genomes | 27.53 |
DLBCL | Schmitz cohort | 22.34 |
DLBCL | Reddy cohort | 10.91 |
DLBCL | Chapuy cohort | 21.37 |
FL | GAMBL genomes | 6.93 |
MCL | GAMBL genomes | 9.00 |
Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
---|---|---|---|---|
BL | No | Yes | 83.783 | 58.309 |
DLBCL | No | Yes | 127.531 | 143.760 |
FL | No | Yes | 63.211 | 142.226 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
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