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ZC3H12A

rdmorin edited this page Jul 4, 2024 · 15 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

ZC3H12A

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
    title Publication timing
2018-05-01 : Chapuy : DLBCL
2018-10-01 : Arthur : DLBCL
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Relevance tier by entity

Entity Tier Description
MCL 2 relevance in MCL not firmly established
DLBCL 1 high-confidence DLBCL gene [@chapuyMolecularSubtypesDiffuse2018b; @arthurGenomewideDiscoverySomatic2018]
FL 2 relevance in FL not firmly established

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 2.68
DLBCL Schmitz cohort 5.96
DLBCL Reddy cohort 3.10
DLBCL Chapuy cohort 4.70
FL GAMBL genomes 0.46

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.000 0.000
DLBCL No No 2.488 18.944
FL No No 0.000 0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

ZC3H12A Expression

References

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