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rdmorin edited this page Jul 3, 2024 · 18 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

NFKB2

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL
      2019-09-05 : Mottok : PMBL
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Relevance tier by entity

Entity Tier Description
PMBL 2 relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b]
DLBCL 3 Retired, Failed QC[@reddyGeneticFunctionalDrivers2017]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 1.53
DLBCL Schmitz cohort 1.49
DLBCL Reddy cohort 1.40
DLBCL Chapuy cohort 2.56

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 1.937 0.00
DLBCL No No 0.861 8.02
FL No No 2.873 0.00

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

NFKB2 Expression

All Mutations

Reddy_2124T Reddy_2525T Reddy_2538T Reddy_2613T Reddy_2637T Reddy_2643T Reddy_2681T Reddy_2761T Reddy_2765T Reddy_2884T Reddy_2918T Reddy_3582T Reddy_3617T Reddy_3639T Reddy_3737T Reddy_3754T Reddy_3825T Reddy_3839T Reddy_3933T Reddy_3936T Reddy_3996T Reddy_695T

References

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