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Automatic local resolution-based sharpening of cryo-EM maps
A new Xmipp method for local sharpening of volumes generated by cryo-EM. The algorithm (LocalDeblur) is based on a local resolution-guided Wiener restoration approach, does not need any prior atomic model and it avoids artificial structure factor corrections.
LocalDeblur requires as input an unfiltered 3D reconstruction Cryo-EM density map and a local resolution map calculated either with MonoRes or Resmap.
Soon at https://www.biorxiv.org/